Usually, you look in the system map and try to locate a metal rich/metal content rich planet. Then you check to see if there are any resource extraction points. After locating them, you drop into them and move to the center, like sit on top of the center and monitor your contact list for wanted ships. Stay around 7KM radius within the center, and always return to it if there are no more ships.
You can reset your instance by logging into the main menu then back in, it will refresh your instance. Be aware that if another player joins your instance, it will also refresh the instance.
A good instance is filled with Conda, Clipper, Dropship, Python. If the first ship/or the first couple of ships you spot are large ships, they will likely continue to spawn large ships in that instance. (Larger ships/ better reward, always scan them with K-warrant since it doubles your profit most of the time. Use energy weapons as much as possible to minimize trips to nearby stations.)
Use your head lights if you are in the dark, watch out for asteroids. Then have fun.