My guess is, no.Wouldn't a huge amount of code have to be written just to effectively handle a dynamic human-focused galaxy? If no player visits a system, nothing changes - no expansions, wars, elections, public holidays . . .
Think about the situation after everything settles down - when no humans have touched any systems for a long time. The final states that everything settles into are ultimately also due to randomized stats of the minor factions. We'd have to look at the code to know what those stats are, but we know they're in there. All you really have to do to make the bubble "dynamic" is periodically reshuffle those stats.
And you can do that using random numbers seeded with, for example, the week of the year. Let's say there are just three stats for each minor faction. You could use the factions ID + the week of the year, as the seed to a random number generator. From that you get your three stats. And you repeat that for every minor faction.
...this plan is undoubtedly way more chaotic than you'd want in practice. Instead of completely reshuffling, you could allow the stats to be modified up or down by small amounts. But you get the idea.