Slopey
Volunteer Moderator
So with my current 1920x1200 monitor for example, getting a pair of 1280x1024 monitors would make sense - http://vignette2.wikia.nocookie.net...024_PLP.jpg/revision/latest?cb=20150701033204
Not as much as 3x 1920x1200 - but I guess it's personal preference (and how much you can be bothered to fiddle with it).
Personally, it would mess with my head having 2 different sized monitors around the central one - when not gaming, I drag windows between all 3 pretty much constantly, and going from bigger to smaller would be a pain (imho).
Nvidia is easier to set up with this sort of stuff than Eyefinity in my experience - if you're (or anyone else is) going the AMD route, have a look at DisplayFusion, which is well worth it.