Lancet study on Hydroxychloroquine across 671 hospitals worldwide, and a population of >96000 patients ( including control group) who got treated within 48 hrs of diagnosis:
Results in short:
- no benefit
- increased deaths
- increased cardiac problems
(Compared to controls.)
This is in agreement with the VA study. Significantly large cohort involved.
Strong evidence against using HOCQ for this purpose, at this dosage. It is hard to justify continuing to try something when the death rate goes up all over the world in many centres, confirmed by 2 studies now.
If it did work, by now we should be able to identify a real benefit vs the controls, but that has not materialized. This is disappointing, as we could really use a break in the fight.
This makes the prophylaxis trial look suspect. If it increases mortality, and some of that group gets the disease(say asymptomatically), is that study going to kill some of them?
(It is still undoubtably better than injecting disinfectant, and NO, I shall never let that one go. It is important to remember how colossally stupid the source of that is, and why it should be permanently discredited in order to save lives. )