One reason why Gene Roddenberry didn't care for the "Warp 12" (and possibly higher speeds) is that it would make the Galaxy smaller in his opinion. That said, I could be persuaded to say yes to this type of idea with a few conditions:
1. Just four of them, one for each quadrant of the galaxy.
2. Locations could either be known or have to be discovered (not sure how that would work, i.e., were these "gates" sent there years ago by the ancient ones, did we employ an old warp drive ship to each quarter, etc, such as a stargate floating in space, etc?).
3. Some type of balance effect, such as damage to the FSD, hull, or both in an amount that makes using it risky enough to make you only want to use it once before landing at a station to do repair (how many limpet controllers do we need to bring again???) or (as has been suggested) a 20% chance of getting to the other location in pieces, i.e., blown up, or so damaged that your first job is to do EVA and repair your ship. Choose wisely; you may wish you had purchased that tool kit from Bob's Hardware on the last station you were at before you left. Duct tape can fix almost anything.
4. Works in one direction only, out of the area and in a counter-clockwise direction, i.e., a trip to Colonia would mean using this method three times and the trip from Colonia to the bubble area would be only in THAT direction, not bubble to Colonia. And see point #3 above. Risky business, these gates. Who ever thought of them didn't think about safety first. The guy should be sued into oblivion.
I can see where some people have been all the way out to the upper right hand part of the galaxy, came back for some reason and want to pick up where they left off without having to schlep all that way back again and would appreciate a "fast travel" method to get back to where they left off. The point Mr. Braben made was that the Galaxy is supposed to be BIG. Such distances should be daunting. But if you want a fast means of travel to a distant area there should be a huge risk involved in using it.
And just think of all the fun we'd have here on the forums after the first 20% of users get to the other end of such a device as space dusk that resembles salt.
But hey, "Risk is part of the game if you want to sit in the big chair" (Admiral James T Kirk, Star Trek Generations).