In that situation? Shields up and run through... at close range most enemies don't track fast enough. You might lose shields and up to 30% health (if there's a half dozen enemies) but you'll come out ok.The thing that irritates me is the NPCs infinite battery life. I tried out lasting some guards when I ran out of ammo but they never move away to charge their suit, blocking my exit route.
Getting pinned with no exit is a no- win situation to fight your way out.