If you manage to get on just after the tick when states have made new systems profitable, sure ... but demand regeneration for core gems was very slow in 3.5 (estimated 1-2 years to fully refill a met demand) ... so playing after a popular play time isn't likely to do very well either.This is when the nerf will happen Only at popular play times... if when you play is not popular play time prices of listed sale locations won't drop quick..
Of course, they could have adjusted those parameters a lot in 3.6 - lower initial demand but faster regeneration would probably be more interesting