Too early to say. The obvious difference that has been seized upon is that EDO won't have ship interiors.
AFAIK we wont have GTA style cities either, more like oases of life in a barren wilderness. The graphics will be different, look at EDO guns, its the Elite brand not a super realistic metal gun. NMS has cartoony style, EDO for me is perfect (Goldilocks syndrome lol) and SC is 'too realistic', for me personally, I want to play a game not a movie...but I don't have VR. But the actual things you can do.
I maybe should have explained better, thinking of possible gameplay that could happen.
Pew Pew - of some variety
Salvage / Transport - of some variety
Explore - find stuff you can 'pick up' and keep and hopefully advance your character somehow.
Discover - leave your name on something for being the first
Roles - afaik there arent set 'careers' or desire for them. The average player would probably automate a few more things not manualise new ones so no Vending Machine Repairer role or that type of thing.
Development - of your character / abilities / weapons and what effect that has
Survival (food & drink)- not intended for EDO, some call for it but not sure its that popular within EDO. Oxygen is a finite commodity on foot in EDO.
Multi Crew - wont have 20 players in a ship, potentially 2+ pilot I think now, maybe 3+ pilot. Daily ships arent built with 20 crew in mind, one person can run any ship in the game by themselves.
A lot of it will be down to the 'reason to', the mission or the story of why you do that thing. But in terms of gameplay activity available?
Pirating - As no ship interior, no physical boarding.
Base Building - not in EDO
I get the impression EDO will be more like Tomb Raider in space than GTA in space if that makes sense. Fortnite and COD aint gonna collapse coz EDO is FPS and neither is SC but will more 'SC til I die' players see enough to make them think again about EDO?