Spoilers ahead:
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Woke up (on my alt) in HIP 22460, but was not docked on the Bright Sentinel any more. I was floating in space, without power, everything dark, no control.
The Proteus Wave had been fired, and it failed spectacularly. The Thargoids are angry.
After a bit my ship regained power, and I tried to look around. I was almost immediately attacked by Thargoids, and barely made the jump to Supercruise.
I wandered the system a bit just looking around. It is full of Thargoids and is now considered a Hazardous Area. Thargoids control the system, apparently.
I returned to the Bright Sentinel to see what I could see. It was on fire, and Thargoids were all around. It wasn't long before they noticed me and shut down my ship's power again.
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This time, when I regained power, I was under serious attack. I did not escape, and my ship was destroyed.
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I was transported to Trevithick Dock, over 400LY away.
Meanwhile, on my Main Account out in the black, all is normal and peaceful.
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So it appears that we now have at least one system that is under Thargoid control. Perhaps they will spread out from there. I guess we'll see.
I heard someone in chat say that Guardian Modules do not function in HIP 22460. I didn't have any with me to check.
The rest of the game appears unaffected, so Thargoid fighting will still be optional, I think.