The thing to do when you get to where the stars get as far apart as your jump range is to make sure you don't jump anywhere without the fuel to jump back, especially if you are doing a boosted jump.
If the system is only reachable in the longest jumping ship in the game using no internals and a small fuel tank that is nearly empty then no one can rescue you.
Definitely. I'd only jump somewhere with 2 times the mats for the relevant jump boost, and knowing the destination was scoopable / have more than twice the amount of fuel for a jump back. I don't do suicide missions
It's probably the mountain-man part of me that does that. It's not about being overly cautious, it's about making sure you don't over-extend yourself unnecessarily to a point where others have to risk themselves to get you home. Knowing your capabilities and your kit is key to that
I've been to the bottom of the Perseus arm, and seen nothing below me, with the system I was in being the last point before the Magellanic clouds. Quite a sight, and quite a profound feeling of being on the edge.