I suppose a lot depends on not only what your used to, but also where you will be using it.
I had the Logitech freedom 2.4 (similar to the extreme 3d pro, but wireless), but it recently died on me, so i have been using my wireless xbox 360 pad, as i tend to play from the couch using my big screen tv, i needed wireless.
I find the xbox pad useful, i can hold it in my hand, even lay down when just grinding or exploring, and i rarely need to touch the keyboard, (i also use voice attack).
With the xbox pad, you can map so many buttons to it. ( i have around 34 different functions on mine)
Yes i fancy trying the x55 or similar, but the cost is too much for me, and i would need to sit at a desk to use it.